منابع مشابه
Endothelial Function Varies According to Insulin Resistance Disease Type Short Title: Insulin Resistance and Vascular Function
Objective: We examined the relationship between insulin resistance and vascular function in three insulin resistant states (type 2 diabetes mellitus, non-HIV lipodystrophic diabetes, and non-diabetic polycystic ovary syndrome (PCOS)) and in healthy controls. Research Design and Methods: The population included 12 women with type 2 diabetes, 6 with lipodystrophic diabetes, 10 with polycystic ova...
متن کاملAndrogens, insulin resistance and vascular disease in men.
Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease. Insulin resistance is the hallmark feature of type 2 diabetes and is also an important component of the metabolic syndrome. There is evidence to suggest that testosterone is an important regulator of insulin sensitivity in men. Observational studies have sho...
متن کاملVascular Insulin Resistance Through Fat
Endothelial dysfunction comprises a number of functional alterations in the vascular endothelium that are associated with diabetes and cardiovascular disease, including changes in vasoregulation, enhanced generation of reactive oxygen intermediates, inflammatory activation and altered barrier function. Hyperglycemia is a characteristic feature of type 1 and type 2 diabetes and plays a pivotal r...
متن کاملMechanisms of Vascular Insulin Resistance
Insulin resistance is characterized by the diminished ability of insulin to initiate intracellular signaling. It is a common manifestation of obesity and a prelude to type 2 diabetes. The primary targets of insulin are skeletal muscle, adipose, and the liver. Impaired insulin signaling in these tissues reduces glucose uptake and promotes a metabolic syndrome that is characterized by elevated le...
متن کاملInsulin resistance: vascular function and exercise
Insulin resistance associated with metabolic syndrome and Type 2 diabetes mellitus is an epidemic metabolic disorder, which increases the risk of cardiovascular complications. Impaired vascular endothelial function is an early marker for atherosclerosis, which causes cardiovascular complications. Both experimental and clinical studies indicate that endothelial dysfunction in vasculatures occurs...
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ژورنال
عنوان ژورنال: Journal of Endocrinology, Metabolism and Diabetes of South Africa
سال: 2004
ISSN: 1608-9677,2220-1009
DOI: 10.1080/16089677.2004.11073590